Mechanisms of inhibitors of mutagenesis and carcinogenesis.

@article{Flora1998MechanismsOI,
  title={Mechanisms of inhibitors of mutagenesis and carcinogenesis.},
  author={S De Flora},
  journal={Mutation research},
  year={1998},
  volume={402 1-2},
  pages={151-8}
}
For a rational implementation of chemoprevention strategies it is essential not only to assess the efficacy and safety of putative inhibitors by using a variety of test systems but also to understand the mechanisms involved. This article proposes a detailed classification of mechanisms along with pertinent examples of agents which may be potentially exploited in the host-addressed prevention of cancer and other mutation-related diseases. The classification, presented in tabulated form, covers a… CONTINUE READING

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