Mechanisms of inactivation of poliovirus by chlorine dioxide and iodine.

@article{Alvarez1982MechanismsOI,
  title={Mechanisms of inactivation of poliovirus by chlorine dioxide and iodine.},
  author={M. E. Alvarez and Robert T. O'brien},
  journal={Applied and environmental microbiology},
  year={1982},
  volume={44 5},
  pages={
          1064-71
        }
}
  • M. E. Alvarez, Robert T. O'brien
  • Published in
    Applied and environmental…
    1982
  • Chemistry, Medicine
  • Chlorine dioxide and iodine inactivated poliovirus more efficiently at pH 10.0 than at pH 6.0. Sedimentation analyses of viruses inactivated by chlorine dioxide and iodine at pH 10.9 showed that viral RNA separated from the capsids, resulting in the conversion of virions from 156S structures to 80S particles. The RNAs release from both chlorine dioxide- and iodine-inactivated viruses cosedimented with intact 35S viral RNA. Both chlorine dioxide and iodine reacted with the capsid proteins of… CONTINUE READING

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