Mechanisms of immunotherapy and surrogate markers.

@article{Till2011MechanismsOI,
  title={Mechanisms of immunotherapy and surrogate markers.},
  author={Stephen Till},
  journal={Allergy},
  year={2011},
  volume={66 Suppl 95},
  pages={
          25-7
        }
}
Understanding mechanisms of inducible antigen-specific tolerance will improve immunotherapy and reveal the most relevant biomarkers for objectively measuring response to immunotherapy in clinical trials and routine practice. Various physiological and laboratory parameters are proposed as biomarkers of an immunological response to vaccines, although their surrogacy for clinical end points is unproven. Examples of physiological biomarkers include suppression of allergen-induced early- and late… CONTINUE READING

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