Mechanisms of immunosuppression: effects of cyclophosphamide on cellular immunity.

Abstract

A course of cyclophosphamide administered to guinea pigs after immunization with mycobacteria led to a transient inhibition of cutaneous hypersenSitiVity to tuberculin protein. This treatment resulted in generalized depletion of lymphoid cells, including lymphopenia, and a substantial reduction in the number of macrophages found in induced peritoneal… (More)

Topics

8 Figures and Tables

Slides referencing similar topics