Mechanisms of glutamate release from astrocytes.

  title={Mechanisms of glutamate release from astrocytes.},
  author={Erik B. Malarkey and Vladimir Parpura},
  journal={Neurochemistry international},
  volume={52 1-2},
Astrocytes can release the excitatory transmitter glutamate which is capable of modulating activity in nearby neurons. This astrocytic glutamate release can occur through six known mechanisms: (i) reversal of uptake by glutamate transporters (ii) anion channel opening induced by cell swelling, (iii) Ca2+-dependent exocytosis, (iv) glutamate exchange via the… CONTINUE READING