Mechanisms of gastro-oesophageal reflux in the ferret.

  title={Mechanisms of gastro-oesophageal reflux in the ferret.},
  author={L Ashley Blackshaw and Esther Staunton and John Dent and Richard H. Holloway and C. H. Malbert},
  journal={Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society},
  volume={10 1},
Transient lower oesophageal sphincter (LOS) relaxation is the major mechanism of gastro-oesophageal reflux in humans--an event unassociated with swallowing. Mechanisms involved in triggering transient LOS relaxation are poorly understood, and their further study requires a small animal model. In this study we aimed to establish methods for prolonged… CONTINUE READING