Mechanisms of erythropoietin production in renal cell carcinoma

@article{Katsuoka2000MechanismsOE,
  title={Mechanisms of erythropoietin production in renal cell carcinoma},
  author={Yoji Katsuoka},
  journal={Clinical and Experimental Nephrology},
  year={2000},
  volume={4},
  pages={286-292}
}
In-vitro and in-vivo experiments performed to determine the mechanisms of erythropoietin (EPO) production in renal cell carcinoma are reviewed. When a human EPO-producing renal cell carcinoma was transplanted into athymic nude mice, EPO produced by the renal cell carcinoma cells autonomously produced erythrocytosis that did not respond to physiologic… CONTINUE READING