Mechanisms of eosinophil cytokine release.

  title={Mechanisms of eosinophil cytokine release.},
  author={Christianne Bandeira-Melo and Peter F. Weller},
  journal={Memorias do Instituto Oswaldo Cruz},
  volume={100 Suppl 1},
Human eosinophils have been demonstrated to contain a multitude of cytokines and chemokines that exist pre-formed within these cells. This content of pre-formed cytokines, with diverse potential biologic activities, provides eosinophils with capabilities distinct from most other leukocytes. The localization of pre-formed cytokines within eosinophils is both within specific granules and associated with substantial numbers of morphologically distinct cytoplasmic vesicles. Stimulation for release… CONTINUE READING