Mechanisms of enhanced insulin sensitivity in endurance-trained athletes: effects on blood flow and differential expression of GLUT 4 in skeletal muscles.

@article{Hardin1995MechanismsOE,
  title={Mechanisms of enhanced insulin sensitivity in endurance-trained athletes: effects on blood flow and differential expression of GLUT 4 in skeletal muscles.},
  author={Dana Sue Hardin and Biagio Azzarelli and Jeanne Edwards and Janet K. Wigglesworth and Lidia Maianu and G Brechtel and A. Johnson and A W Harris J J Misiewicz J H Baron and W Timothy Garvey},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1995},
  volume={80 8},
  pages={2437-46}
}
Exercise is associated with increased insulin sensitivity. To better understand mechanisms that could be responsible for this association, we studied seven controls and seven endurance-trained athletes. A 600 mU/m2.min hyperinsulinemic euglycemic glucose clamp with the limb balance technique assessed insulin sensitivity as whole body glucose uptake (WBGU) and leg glucose uptake (LGU). Indirect calorimetry and hemodynamic measurements, such as leg blood flow (LBF) and cardiac output, were… CONTINUE READING

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