Mechanisms of drug resistance in Mycobacterium tuberculosis.

  title={Mechanisms of drug resistance in Mycobacterium tuberculosis.},
  author={M. Wade and Y. Zhang},
  journal={Frontiers in bioscience : a journal and virtual library},
  • M. Wade, Y. Zhang
  • Published 2004
  • Biology, Medicine
  • Frontiers in bioscience : a journal and virtual library
  • Tuberculosis is a worldwide health problem posing increasing threat with the spread of HIV infection and drug resistant Mycobacterium tuberculosis strains. Consequently, control of this disease has become a significant challenge despite the availability of chemotherapy and BCG vaccine. Drug resistance for all first-line anti-tuberculosis agents and some second-line agents has been observed. Moreover, the occurrence of strains of M. tuberculosis resistant to multiple anti-tuberculosis drugs is… CONTINUE READING
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