Mechanisms of drug action and drug resistance in Leishmania as basis for therapeutic target identification and design of antileishmanial modulators.

@article{Loiseau2006MechanismsOD,
  title={Mechanisms of drug action and drug resistance in Leishmania as basis for therapeutic target identification and design of antileishmanial modulators.},
  author={Philippe Marie Loiseau and Christian Bories},
  journal={Current topics in medicinal chemistry},
  year={2006},
  volume={6 5},
  pages={
          539-50
        }
}
The control of Leishmania infections relies primarily on chemotherapy. The arsenal of drugs available against Leishmania infections is limited and includes pentavalent antimonials, pentamidine, amphotericin B, miltefosine, paromomycin, allopurinol, and few other drugs at various stages of their development process. Knowledge about action and resistance… CONTINUE READING