Mechanisms of disease: Receptor traffic — parkin rules

@article{Flight2006MechanismsOD,
  title={Mechanisms of disease: Receptor traffic — parkin rules},
  author={Monica Hoyos Flight},
  journal={Nature Reviews Molecular Cell Biology},
  year={2006},
  volume={7},
  pages={625-625}
}
...a potential link between acetylCoA pools, metabolism, ageing and histone modifications. Four new studies provide a potential link between acetyl-CoA pools, metabolism, ageing and histone modifications. This link might be mediated by sirtuin deacetylases, which have previously been implicated in ageing and metabolism. Histone acetylation is important for many cellular processes including gene expression and DNA repair. Given that all known histone acetyltransferases use acetyl-CoA in the… CONTINUE READING