Mechanisms of deep brain stimulation: excitation or inhibition.

@article{Vitek2002MechanismsOD,
  title={Mechanisms of deep brain stimulation: excitation or inhibition.},
  author={Jerrold L. Vitek},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2002},
  volume={17 Suppl 3},
  pages={S69-72}
}
  • Jerrold L. Vitek
  • Published 2002 in
    Movement disorders : official journal of the…
There is little debate that deep brain stimulation (DBS) has been an effective tool in the treatment of Parkinson's disease as well as other movement disorders. There remains however, considerable debate concerning the mechanism(s) underlying its beneficial effect. The comparable effect of stimulation to ablation in the thalamus on tremor, and in the subthalamic nucleus (STN) and internal segment of the globus pallidus (GPi) on the motor signs associated with PD, have led many investigators to… CONTINUE READING
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