Corpus ID: 85865235

Mechanisms of deadenylation regulation under different cellular conditions

@inproceedings{Zhang2014MechanismsOD,
  title={Mechanisms of deadenylation regulation under different cellular conditions},
  author={X. Zhang},
  year={2014}
}

• X. Zhang
• Published 2014
• Biology

Mechanisms of Deadenylation Regulation Under Different Cellular Conditions By Xiaokan Zhang Adviser: Professor Frida Esther Kleiman Control of gene expression by regulating mRNA stability after DNA damage has the potential to contribute to the cells rapid response to stress. The main focus of this dissertation is to elucidate the role(s) of nuclear PARN deadenylase in controlling mRNA stability, hence gene expression, of factors in the p53 signaling pathway during the DNA damage response (DDR… Expand

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