Mechanisms of cytochrome P450 induction.

Abstract

Cytochrome P450s (CYPs) are important heme-containing proteins that play important roles in the metabolism of xenobiotics and endogenous compounds. The oxidative metabolisms of drugs, environmental chemicals, hormones, and fatty acids by CYP enzymes are critical pathways aiding in their excretion from the body, but in some cases metabolism may lead to… (More)

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Cite this paper

@article{Tompkins2007MechanismsOC, title={Mechanisms of cytochrome P450 induction.}, author={Leslie M Tompkins and Andrew D. Wallace}, journal={Journal of biochemical and molecular toxicology}, year={2007}, volume={21 4}, pages={176-81} }