Mechanisms of chromium toxicity, carcinogenicity and allergenicity: Review of the literature from 1985 to 2000

@article{Dayan2001MechanismsOC,
  title={Mechanisms of chromium toxicity, carcinogenicity and allergenicity: Review of the literature from 1985 to 2000},
  author={Anthony D. Dayan and Alan J. Paine},
  journal={Human and Experimental Toxicology},
  year={2001},
  volume={20},
  pages={439 - 451}
}
  • A. Dayan, A. Paine
  • Published 2001
  • Chemistry, Medicine
  • Human and Experimental Toxicology
Laboratory and clinical reports about the pathogenesis of the carcinogenicity and allergenicity of chromium compounds published between 1985 and 2000 have been reviewed as a basis for consideration of the pathogenetic mechanisms involved. There is good evidence from the clinic and the laboratory that Cr[VI] is the ion responsible for most of the toxic actions, although much of the under lying molecular damage may be due to its intracellular reduction to the even more highly reactive and short… Expand
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