Mechanisms of cholesterol-lowering effects of dietary insoluble fibres: relationships with intestinal and hepatic cholesterol parameters.

@article{Bennekum2005MechanismsOC,
  title={Mechanisms of cholesterol-lowering effects of dietary insoluble fibres: relationships with intestinal and hepatic cholesterol parameters.},
  author={Ari{\"e}tte M van Bennekum and David V X Nguyen and Georg Schulthess and Helmut Hauser and Michael C Phillips},
  journal={The British journal of nutrition},
  year={2005},
  volume={94 3},
  pages={331-7}
}
Fibres with a range of abilities to perturb cholesterol homeostasis were used to investigate how the serum cholesterol-lowering effects of insoluble dietary fibres are related to parameters of intestinal cholesterol absorption and hepatic cholesterol homeostasis in mice. Cholestyramine, chitosan and cellulose were used as examples of fibres with high, intermediate and low bile acid-binding capacities, respectively. The serum cholesterol levels in a control group of mice fed a high fat/high… CONTINUE READING
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