Mechanisms of cell killing in photodynamic therapy using a novel in vivo drug/in vitro light culture system.

@article{Hampton1992MechanismsOC,
  title={Mechanisms of cell killing in photodynamic therapy using a novel in vivo drug/in vitro light culture system.},
  author={James A Hampton and Steven H. Selman},
  journal={Photochemistry and photobiology},
  year={1992},
  volume={56 2},
  pages={235-43}
}
Photodynamic therapy of certain neoplasms has emerged as a promising form of cancer treatment. This type of therapy involves the exogenous administration of a photosensitizer with subsequent exposure to light. The ensuing photochemical reaction results in destruction of the tumor. Whether tumor cells are destroyed directly by the photodynamic treatment or indirectly as a result of destruction of the tumor microvascular bed is unknown. To address this question, methods were adapted to test… CONTINUE READING