Mechanisms of c-reactive protein up-regulation in arterialized vein grafts.

@article{Gulkarov2006MechanismsOC,
  title={Mechanisms of c-reactive protein up-regulation in arterialized vein grafts.},
  author={Iosif Gulkarov and Giuseppe Pintucci and Katja Bohmann and Paul C. Saunders and Raymond F. Sullivan and Giovanni Ferrari and Paolo Mignatti and Aubrey C. Galloway},
  journal={Surgery},
  year={2006},
  volume={139 2},
  pages={254-62}
}
BACKGROUND C-reactive protein (CRP), an acute phase reactant, is an independent predictor of coronary artery syndromes and a mediator of the vascular response to injury. CRP has been found in arterialized vein grafts and has been linked to atherogenesis; however, its involvement in vein graft early failure or intimal hyperplasia has not been assessed. This study was designed to investigate the mechanism(s) of CRP up-regulation in arterialized vein grafts. METHODS Carotid artery bypass with… CONTINUE READING