Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis.

@article{Bannerman2003MechanismsOB,
  title={Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis.},
  author={Douglas D. Bannerman and Simeon E. Goldblum},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2003},
  volume={284 6},
  pages={
          L899-914
        }
}
  • D. Bannerman, S. Goldblum
  • Published 1 June 2003
  • Biology, Medicine
  • American journal of physiology. Lung cellular and molecular physiology
Gram-negative bacterial sepsis remains a common, life-threatening event. The prognosis for patients who develop sepsis-related complications, including the development of acute respiratory distress syndrome (ARDS), remains poor. A common finding among patients and experimental animals with sepsis and ARDS is endothelial injury and/or dysfunction. A component of the outer membrane of gram-negative bacteria, lipopolysaccharide (LPS) or endotoxin, has been implicated in the pathogenesis of much of… 

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...

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