Mechanisms of azole resistance in a clinical isolate of Candida tropicalis.

@article{Vandeputte2005MechanismsOA,
  title={Mechanisms of azole resistance in a clinical isolate of Candida tropicalis.},
  author={Patrick Vandeputte and G{\'e}rald Larcher and Thierry Berg{\`e}s and Gilles R{\'e}nier and Dominique Chabasse and J B Bouchara},
  journal={Antimicrobial agents and chemotherapy},
  year={2005},
  volume={49 11},
  pages={4608-15}
}
Azole resistance has been insufficiently investigated in the yeast Candida tropicalis. Here we determined the molecular mechanisms responsible for azole resistance in a clinical isolate of this pathogenic yeast. Antifungal susceptibility testing performed by a disk diffusion method showed resistance or markedly decreased susceptibility to azoles, which was confirmed by determination of MICs. Considering the relationship between azole susceptibility and the respiration reported for other yeast… CONTINUE READING
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Antifungal resistance : the clinical front

  • A. Polak
  • Oncology
  • 2004

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