Mechanisms of autoimmune disease in the testis and ovary.

  title={Mechanisms of autoimmune disease in the testis and ovary.},
  author={Kenneth S Tung and Cory Teuscher},
  journal={Human reproduction update},
  volume={1 1},
This article reviews recent research on autoimmune diseases of the testis and ovary based on two experimental approaches for induction of autoimmune diseases of the gonads (immunization with testis or ovary antigen, usually with adjuvant, and deliberate alteration of the immune system in normal animals, without injecting antigen or adjuvant). It has been found that the local testicular immunoregulatory environment partially impedes autoimmune responses to ontogenic testis antigens and… CONTINUE READING