Mechanisms of antibacterial action of three monoterpenes.

  title={Mechanisms of antibacterial action of three monoterpenes.},
  author={Domenico Trombetta and F Castelli and Maria Grazia Sarpietro and Vincenza Venuti and M. Cristani and Claudia Daniele and Antonella Saija and Gabriela Mazzanti and Giuseppe Giovanni Bisignano},
  journal={Antimicrobial agents and chemotherapy},
  volume={49 6},
In the present paper, we report the antimicrobial efficacy of three monoterpenes [linalyl acetate, (+)menthol, and thymol] against the gram-positive bacterium Staphylococcus aureus and the gram-negative bacterium Escherichia coli. For a better understanding of their mechanisms of action, the capability of these three monoterpenes to damage biomembranes was evaluated by monitoring the release, following exposure to the compounds under study, of the water-soluble fluorescent marker… CONTINUE READING