Mechanisms of alcohol-mediated CD4+ T lymphocyte death: relevance to HIV and HCV pathogenesis.

@article{Barve2002MechanismsOA,
  title={Mechanisms of alcohol-mediated CD4+ T lymphocyte death: relevance to HIV and HCV pathogenesis.},
  author={Shirish S. Barve and Sujata V Kelkar and Leila Gobejishvilli and Swati Joshi-Barve and C J Mcclain},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2002},
  volume={7},
  pages={d1689-96}
}
Clinical and experimental studies have demonstrated that excessive alcohol consumption can result in impairment of the immune system, and can impact several immune functions including immune tolerance and host defense against opportunistic infections, and development of certain tumors. Although multiple factors are involved in the effects of ethanol on the immune system, several studies implicate chronic activation of immune cells and impairment of thymus-derived lymphocytes (T lymphocytes… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 114 references

Oxidative stress in human immunodeficiency virus infection

  • N.Israel, M.A.Gougerot-Pocidalo
  • Cell Mol Life Sci 53, 864-870
  • 1997
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…