Mechanisms of airway remodeling in asthma.

@article{Tagaya2007MechanismsOA,
  title={Mechanisms of airway remodeling in asthma.},
  author={Etsuko Tagaya and Jun Tamaoki},
  journal={Allergology international : official journal of the Japanese Society of Allergology},
  year={2007},
  volume={56 4},
  pages={331-40}
}
Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known as airway remodeling and consequently airway obstruction that is not fully reversible and progressive loss of lung function over time. It is generally accepted that airway remodeling is closely related to progression of airway hyperresponsiveness, and the severity of asthma. The structural changes… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 75 references

EosinophilAirway Remodeling in Asthma

EM Minshall, DY Leung, RJ Martin
Allergology International Vol 56, • 2007

LTD-4 induces matrix metalloproteinase-1 which function as IGFBP protease in airway smooth muscle cells

R B67 Rajah, S Nunn, D Herrick, MM Grunstein, P. Cohen
Am. J. Physiol. Lung Cell. Mol. Physiol. 1996;271:L1014Tagaya E et al • 2007

Fc epsilon R Imediated amphiregulin production by human mast cells increases mucin gene expression in epithelial cells

S Okumura, H Sagara, T Fukuda
J. Allergy Clin. Immunol • 2005

Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2005

Similar Papers

Loading similar papers…