Mechanisms of airway remodeling in asthma.

  title={Mechanisms of airway remodeling in asthma.},
  author={Etsuko Tagaya and Jun Tamaoki},
  journal={Allergology international : official journal of the Japanese Society of Allergology},
  volume={56 4},
Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known as airway remodeling and consequently airway obstruction that is not fully reversible and progressive loss of lung function over time. It is generally accepted that airway remodeling is closely related to progression of airway hyperresponsiveness, and the severity of asthma. The structural changes… CONTINUE READING

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