Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview.

@article{Correia2008MechanismsOA,
  title={Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview.},
  author={S{\'o}nia Catarina Correia and Cristina Carvalho and Maria Sancha Santos and Raquel Seiça and Catarina Resende de Oliveira and Paula I Moreira},
  journal={Mini reviews in medicinal chemistry},
  year={2008},
  volume={8 13},
  pages={
          1343-54
        }
}
Type 2 diabetes is a major health problem associated with excess mortality and morbidity. Vascular complications are one of the most serious consequences of this disorder. Moreover, type 2 diabetes is also a risk factor for cerebral complications, including cognitive impairment and dementia. However, it has been shown that tight glycemic control contributes to reduce the incidence of diabetes-associated complications. Metformin is a potent antihyperglycemic agent widely used in the management… CONTINUE READING

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