Mechanisms of action of extracorporeal photochemotherapy in the control of GVHD: involvement of dendritic cells

Abstract

Despite the fact that extracorporal photochemotherapy (ECP) is now broadly used for the treatment of graft versus host disease or T-cell lymphomas, the mechanisms of its action remain enigmatic. This work provides a synthesis of the main results suggesting the initiation by ECP of an immune reaction responsible for the down modulation of pathogenic T-cell functions, with a special focus on the role of dendritic cells in this phenomenon.

DOI: 10.1038/sj.leu.2403114

Cite this paper

@article{Plumas2003MechanismsOA, title={Mechanisms of action of extracorporeal photochemotherapy in the control of GVHD: involvement of dendritic cells}, author={J{\"{o}el Plumas and Olivier Manches and Laurence Chaperot}, journal={Leukemia}, year={2003}, volume={17}, pages={2061-2062} }