Mechanisms of action of estrogen in the brain: insights from human neuroimaging and psychopharmacologic studies.

@article{Maki2009MechanismsOA,
  title={Mechanisms of action of estrogen in the brain: insights from human neuroimaging and psychopharmacologic studies.},
  author={Pauline M. Maki and Julie Dumas},
  journal={Seminars in reproductive medicine},
  year={2009},
  volume={27 3},
  pages={250-9}
}
Use of estrogen therapy in the perimenopausal and postmenopausal periods has been shown in several clinical trials to help women maintain a premenopausal level of cognitive function. What is not yet fully understood is how the neurobiological effects of estrogen contribute to these cognitive effects. This review explores data from two related bodies of human literature that provide compelling evidence in support of the biological plausibility that estrogen treatment can benefit cognition. The… CONTINUE READING

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