Mechanisms of action of BCL6 during germinal center B cell development

Abstract

The transcriptional repressor B cell lymphoma 6 (BCL6) controls a large transcriptional network that is required for the formation and maintenance of germinal centers (GC). GC B cells represent the normal counterpart of most human B-cell lymphomas, which are often characterized by deregulated BCL6 expression or BCL6-mediated pathways. BCL6 suppresses gene… (More)
DOI: 10.1007/s11427-015-4919-z

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@article{Huang2015MechanismsOA, title={Mechanisms of action of BCL6 during germinal center B cell development}, author={Chuanxin Huang and Ari Melnick}, journal={Science China Life Sciences}, year={2015}, volume={58}, pages={1226-1232} }