Mechanisms of action for the commonly used antiepileptic drugs: relevance to antiepileptic drug-associated neurobehavioral adverse effects.

@article{Sankar2004MechanismsOA,
  title={Mechanisms of action for the commonly used antiepileptic drugs: relevance to antiepileptic drug-associated neurobehavioral adverse effects.},
  author={R Ramesh Sankar and Gregory L. Holmes},
  journal={Journal of child neurology},
  year={2004},
  volume={19 Suppl 1},
  pages={S6-14}
}
Antiepileptic drugs exert their anticonvulsant effects by interfering with brain processes that involve structures that are also involved in learning, memory, and emotional behavior. Thus, modulation of ion channels, neurotransmitters, second messengers, and other processes by antiepileptic drugs, although helpful in controlling seizures, can interfere with normal brain function in undesired ways. The specific mechanism(s) of action of an antiepileptic drug can increase the risk for particular… CONTINUE READING

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