Mechanisms of action, physiological effects, and complications of hypothermia

  title={Mechanisms of action, physiological effects, and complications of hypothermia},
  author={K. Polderman},
  journal={Critical Care Medicine},
  • K. Polderman
  • Published 2009
  • Medicine
  • Critical Care Medicine
  • Background:Mild to moderate hypothermia (32–35°C) is the first treatment with proven efficacy for postischemic neurological injury. In recent years important insights have been gained into the mechanisms underlying hypothermia's protective effects; in addition, physiological and pathophysiological changes associated with cooling have become better understood. Objective:To discuss hypothermia's mechanisms of action, to review (patho)physiological changes associated with cooling, and to discuss… CONTINUE READING
    848 Citations

    Paper Mentions

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