Mechanisms of action, physiological effects, and complications of hypothermia

K. Polderman

DOI:10.1097/CCM.0b013e3181aa5241

Corpus ID: 6494903

Mechanisms of action, physiological effects, and complications of hypothermia

@article{Polderman2009MechanismsOA,
  title={Mechanisms of action, physiological effects, and complications of hypothermia},
  author={K. Polderman},
  journal={Critical Care Medicine},
  year={2009},
  volume={37},
  pages={S186-S202}
}

K. Polderman

Published 2009

Medicine

Critical Care Medicine

Background:Mild to moderate hypothermia (32–35°C) is the first treatment with proven efficacy for postischemic neurological injury. In recent years important insights have been gained into the mechanisms underlying hypothermia's protective effects; in addition, physiological and pathophysiological changes associated with cooling have become better understood. Objective:To discuss hypothermia's mechanisms of action, to review (patho)physiological changes associated with cooling, and to discuss… CONTINUE READING

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