Mechanisms of acid resistance due to the urease system of Helicobacter pylori.

@article{Scott2002MechanismsOA,
  title={Mechanisms of acid resistance due to the urease system of Helicobacter pylori.},
  author={David R Scott and Elizabeth A. Marcus and David L. Weeks and George Sachs},
  journal={Gastroenterology},
  year={2002},
  volume={123 1},
  pages={187-95}
}
BACKGROUND & AIMS Helicobacter pylori, a neutralophile, uses acid neutralization by urease to combat gastric acidity, allowing gastric colonization. Both acute and chronic acid resistance mechanisms are present. Acute mechanisms of acid adaptation could be due to surface urease, increased inner-membrane urea permeability via UreI, or both. Slower mechanisms may involve increased nickel insertion into apoenzyme, posttranscriptional regulation, or increased enzyme synthesis. The aim of this study… CONTINUE READING

From This Paper

Topics from this paper.
55 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

Similar Papers

Loading similar papers…