Mechanisms of X Chromosome Dosage Compensation

@inproceedings{Ercan2015MechanismsOX,
  title={Mechanisms of X Chromosome Dosage Compensation},
  author={Sevinç Ercan},
  booktitle={Journal of genomics},
  year={2015}
}
In many animals, males have one X and females have two X chromosomes. The difference in X chromosome dosage between the two sexes is compensated by mechanisms that regulate X chromosome transcription. Recent advances in genomic techniques have provided new insights into the molecular mechanisms of X chromosome dosage compensation. In this review, I summarize our current understanding of dosage imbalance in general, and then review the molecular mechanisms of X chromosome dosage compensation… CONTINUE READING

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