Mechanisms of Synergy Between Alcohol and Hepatitis C Virus

@article{Singal2007MechanismsOS,
  title={Mechanisms of Synergy Between Alcohol and Hepatitis C Virus},
  author={Ashwani K. Singal and Bhupinder S. Anand},
  journal={Journal of Clinical Gastroenterology},
  year={2007},
  volume={41},
  pages={761-772}
}
  • A. Singal, B. Anand
  • Published 1 September 2007
  • Medicine
  • Journal of Clinical Gastroenterology
Background Since the discovery of the hepatitis C virus (HCV), extensive literature has emerged on alcohol and HCV interaction. Goal To understand the impact of alcohol and HCV infection on the severity of liver disease and the mechanisms of interaction between the two. Study Of 1269 articles (1991 to 2006) searched through MEDLINE and cited cross references, 133 were thoroughly reviewed to assess: (a) prevalence of combined alcohol use and HCV, (b) severity of liver disease (c) treatment… Expand
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Ethanol exposure potentiates the suppressive effects of HCV on innate immunity, which activates viral spread in the liver and finally, leads to impairments in adaptive immunity. Expand
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Clinical and basic research findings presented here summarize key scientific findings with the aim of highlighting potential areas for new therapies and identifying ways of optimizing current treatments for alcoholics with HCV infection. Expand
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Aims To provide an overview of published literature on the interaction of alcohol and hepatitis C virus (HCV) in the accelerated progression of liver disease to cirrhosis as relates toExpand
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  • Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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