Mechanisms of RhoGDI2 mediated lung cancer epithelial-mesenchymal transition suppression.

BACKGROUND The aim of this study was to evaluate the function of RhoGDI2 in lung cancer epithelial-mesenchymal transition (EMT) process and to illustrate the underlying mechanisms that will lead to improvement of lung cancer treatment. METHODS The RhoGDI2 knock-down and overexpressing A549 cell lines were first constructed. The influence of RhoGDI2 on… CONTINUE READING