Mechanisms of Regulation of Olfactory Transduction and Adaptation in the Olfactory Cilium

@inproceedings{Antunes2014MechanismsOR,
  title={Mechanisms of Regulation of Olfactory Transduction and Adaptation in the Olfactory Cilium},
  author={Gabriela Antunes and Ana M. Sebasti{\~a}o and Fabio Marques Simoes de Souza},
  booktitle={PloS one},
  year={2014}
}
Olfactory adaptation is a fundamental process for the functioning of the olfactory system, but the underlying mechanisms regulating its occurrence in intact olfactory sensory neurons (OSNs) are not fully understood. In this work, we have combined stochastic computational modeling and a systematic pharmacological study of different signaling pathways to investigate their impact during short-term adaptation (STA). We used odorant stimulation and electroolfactogram (EOG) recordings of the… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 148 REFERENCES

Beta-arrestin2-mediated internalization of mammalian odorant receptors.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2006
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

COPASI - a COmplex PAthway SImulator

  • Bioinformatics
  • 2006
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL