Mechanisms of Physical Activity Limitation in Chronic Lung Diseases

  title={Mechanisms of Physical Activity Limitation in Chronic Lung Diseases},
  author={Ioannis A Vogiatzis and George Zakynthinos and Vasileios Andrianopoulos},
  booktitle={Pulmonary medicine},
In chronic lung diseases physical activity limitation is multifactorial involving respiratory, hemodynamic, and peripheral muscle abnormalities. The mechanisms of limitation discussed in this paper relate to (i) the imbalance between ventilatory capacity and demand, (ii) the imbalance between energy demand and supply to working respiratory and peripheral muscles, and (iii) the factors that induce peripheral muscle dysfunction. In practice, intolerable exertional symptoms (i.e., dyspnea) and/or… CONTINUE READING


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