Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals

@inproceedings{Bosch2015MechanismsOP,
  title={Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals},
  author={Ricardo Bosch and Neena Philips and Jorge A. Su{\'a}rez-P{\'e}rez and Angeles Juarranz and Avani Devmurari and Jovinna Chalensouk-Khaosaat and Salvador Gonz{\'a}lez},
  booktitle={Antioxidants},
  year={2015}
}
Photoaging and photocarcinogenesis are primarily due to solar ultraviolet (UV) radiation, which alters DNA, cellular antioxidant balance, signal transduction pathways, immunology, and the extracellular matrix (ECM). The DNA alterations include UV radiation induced thymine-thymine dimers and loss of tumor suppressor gene p53. UV radiation reduces cellular… CONTINUE READING