Mechanisms of Pefloxacin-Induced Pain

Abstract

In electrophysiological and behavioral experiments on rats we studied the effects of pefloxacin, a member of fluoroquinolone family, on the nociceptive system. Intraperitoneal injection of pefloxacin (80 mg/kg) decreased the thresholds of nociceptive response to noxious stimulation in the hot-plate test. In addition, it decreased the threshold of the late… (More)
DOI: 10.1023/B:BEBM.0000035122.45148.93

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