Mechanisms of P/CAF auto-acetylation.

  title={Mechanisms of P/CAF auto-acetylation.},
  author={Helena Santos-Rosa and Ester Valls and Tony Kouzarides and Marian A Mart{\'i}nez-Balb{\'a}s},
  journal={Nucleic acids research},
  volume={31 15},
P/CAF is a histone acetyltransferase enzyme which was originally identified as a CBP/p300-binding protein. In this manuscript we report that human P/CAF is acetylated in vivo. We find that P/CAF is acetylated by itself and by p300 but not by CBP. P/CAF acetylation can be an intra- or intermolecular event. The intermolecular acetylation requires the N… CONTINUE READING