Mechanisms of Neuroimmunity and Neurodegeneration Associated with HIV-1 Infection and AIDS

@article{Kaul2006MechanismsON,
  title={Mechanisms of Neuroimmunity and Neurodegeneration Associated with HIV-1 Infection and AIDS},
  author={Marcus Kaul and Stuart Lipton},
  journal={Journal of Neuroimmune Pharmacology},
  year={2006},
  volume={1},
  pages={138-151}
}
Infection with the human immunodeficiency virus-1 (HIV-1) and acquired immunodeficiency syndrome (AIDS) are a persistent health problem worldwide. HIV-1 seems to enter the brain very soon after peripheral infection and can induce severe and debilitating neurological problems that include behavioral abnormalities, motor dysfunction, and frank dementia. Infected peripheral immune-competent cells, in particular macrophages, appear to infiltrate the CNS and provoke a neuropathological response… CONTINUE READING

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