Mechanisms of NH4+ and NH3 transport during hypokalemia.

  title={Mechanisms of NH4+ and NH3 transport during hypokalemia.},
  author={Susan M. Wall},
  journal={Acta physiologica Scandinavica},
  volume={179 4},
Along the collecting duct, secretion of ammonium (NH) is thought to occur through active H+ secretion in parallel with the non-ionic diffusion of ammonia (NH3). Thus NH3 is secreted into the collecting duct lumen down its concentration gradient. Moreover, the low NH permeability and high NH3 permeability observed in collecting duct epithelia minimizes back diffusion of NH. In general, an increase in the NH3 concentration gradient between the interstitium and the collecting duct lumen correlates… CONTINUE READING

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