Mechanisms of Mycotoxin-Induced Neurotoxicity through Oxidative Stress-Associated Pathways

@inproceedings{Doi2011MechanismsOM,
  title={Mechanisms of Mycotoxin-Induced Neurotoxicity through Oxidative Stress-Associated Pathways},
  author={Kunio Doi and Koji Uetsuka},
  booktitle={International journal of molecular sciences},
  year={2011}
}
Among many mycotoxins, T-2 toxin, macrocyclic trichothecenes, fumonisin B(1) (FB(1)) and ochratochin A (OTA) are known to have the potential to induce neurotoxicity in rodent models. T-2 toxin induces neuronal cell apoptosis in the fetal and adult brain. Macrocyclic trichothecenes bring about neuronal cell apoptosis and inflammation in the olfactory epithelium and olfactory bulb. FB(1) induces neuronal degeneration in the cerebral cortex, concurrent with disruption of de novo ceramide synthesis… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS