Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions.

@article{Jaeschke2006MechanismsOL,
  title={Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions.},
  author={Hartmut Jaeschke},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2006},
  volume={290 6},
  pages={G1083-8}
}
  • Hartmut Jaeschke
  • Published 2006 in
    American journal of physiology. Gastrointestinal…
Polymorphonuclear leukocytes (neutrophils) are a vital part of the innate immune response to microbial infections and tissue trauma, e.g., ischemia-reperfusion injury, in many organs including the liver. However, an excessive inflammatory response can lead to a dramatic aggravation of the existing injury. To design interventions, which selectively target the detrimental effects of neutrophils, a detailed understanding of the pathophysiology is critical. Systemic or local exposure to… CONTINUE READING
180 Citations
24 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 180 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Similar Papers

Loading similar papers…