Mechanisms of LDL oxidation.

  title={Mechanisms of LDL oxidation.},
  author={Hiroshi Yoshida and Reiko Kisugi},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={411 23-24},
BACKGROUNDS Many lines of evidence suggest that oxidized low-density lipoprotein (LDL) is implicated in the pathogenesis of atherosclerotic vascular diseases. This review summarizes a diversity of mechanisms proposed for LDL oxidation serving for the so-called "LDL oxidation hypothesis of atherogenesis". METHODS AND RESULTS We investigated the literature and our research results related to mechanisms of LDL oxidation and its atherogenesis. LDL oxidation is catalyzed by transition metal ions… CONTINUE READING
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