Mechanisms of Endothelial Dysfunction in Resistance Arteries from Patients with End-Stage Renal Disease

@inproceedings{Luksha2012MechanismsOE,
  title={Mechanisms of Endothelial Dysfunction in Resistance Arteries from Patients with End-Stage Renal Disease},
  author={Leanid Luksha and Peter Stenvinkel and Folke Hammarqvist and Juan Jes{\'u}s Carrero and Sandra T Davidge and Karolina R. Kublickiene},
  booktitle={PloS one},
  year={2012}
}
The study focuses on the mechanisms of endothelial dysfunction in the uremic milieu. Subcutaneous resistance arteries from 35 end-stage renal disease (ESRD) patients and 28 matched controls were studied ex-vivo. Basal and receptor-dependent effects of endothelium-derived factors, expression of endothelial NO synthase (eNOS), prerequisites for myoendothelial gap junctions (MEGJ), and associations between endothelium-dependent responses and plasma levels of endothelial dysfunction markers were… CONTINUE READING

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