Mechanisms of Disease: astrocytes in neurodegenerative disease

  title={Mechanisms of Disease: astrocytes in neurodegenerative disease},
  author={Nicholas J. Maragakis and Jeffrey D Rothstein},
  journal={Nature Clinical Practice Neurology},
The term neurodegenerative disease refers to the principal pathology associated with disorders such as amyotrophic lateral sclerosis, Alzheimer's disease, Huntington's disease and Parkinson's disease, and it is presumed that neurodegeneration results in the clinical findings seen in patients with these diseases. Decades of pathological and physiological studies have focused on neuronal abnormalities in these disorders, but it is becoming increasingly evident that astrocytes are also important… CONTINUE READING
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