Mechanisms of Disease: Toll-like receptors in cardiovascular disease


The innate immune system detects highly conserved, relatively invariant structural motifs of pathogens. Toll-like receptors (TLRs) have been identified as the primary innate immune receptors. TLRs distinguish between different patterns of pathogens and activate a rapid innate immune response; however, TLRs can also be activated by host-derived molecules. In… (More)
DOI: 10.1038/ncpcardio0938


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@article{Frantz2007MechanismsOD, title={Mechanisms of Disease: Toll-like receptors in cardiovascular disease}, author={Stefan Frantz and Georg Ertl and Johann Bauersachs}, journal={Nature Clinical Practice Cardiovascular Medicine}, year={2007}, volume={4}, pages={444-454} }