Mechanisms of DNA Transposition.

  title={Mechanisms of DNA Transposition.},
  author={Alison Burgess Hickman and Fred Dyda},
  journal={Microbiology spectrum},
  volume={3 2},
DNA transposases use a limited repertoire of structurally and mechanistically distinct nuclease domains to catalyze the DNA strand breaking and rejoining reactions that comprise DNA transposition. Here, we review the mechanisms of the four known types of transposition reactions catalyzed by (1) RNase H-like transposases (also known as DD(E/D) enzymes); (2… CONTINUE READING