Mechanisms of Cell Death in Acute Liver Failure

  title={Mechanisms of Cell Death in Acute Liver Failure},
  author={Heike Bantel and Klaus Schulze-Osthoff},
  booktitle={Front. Physio.},
Acute liver failure (ALF) can be the consequence of various etiologies, that might vary between different geographic regions. Most frequent are intoxications with acetaminophen, viral hepatitis, or liver damage of unknown origin. ALF occurs when the extent of hepatocyte death exceeds the regenerative capacity of the liver. The mode of liver cell death that is predominantly induced in ALF, i.e., apoptosis or necrosis, is still controversial and presumably determined by the etiology, duration… CONTINUE READING
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